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Peptide and hormone therapies are administered with ultra-fine needles, typically ranging from 27G to 31G. Subcutaneous injections generally use a short 5/16" needle, while slightly longer 5/8" options may be used for amino acid blends or shallow intramuscular delivery. For reference, these needles are about the size of a pencil eraser to the width of a dime—designed for comfort, precision, and ease of self-administration.
You have flexibility in where your therapy is administered. Most treatments are delivered into the subcutaneous layer—just beneath the skin—using a fine, short needle for a comfortable and precise experience. In some cases, intramuscular (IM) injections are required, utilizing a slightly longer needle to ensure accurate delivery into the muscle, depending on individual anatomy. Your care team will guide you in choosing the most effective and comfortable option for your protocol.
Subcutaneous injections are administered into areas of soft, pinchable fat—typically the lower abdomen (2–3 inches from the navel), outer thigh, back of the upper arm, or lower back near the flanks. It’s important to rotate sites regularly to prevent irritation and ensure optimal absorption. Intramuscular injections are delivered into deeper muscle tissue, most commonly the upper outer glute (ventrogluteal), deltoid (shoulder), or outer thigh (vastus lateralis). Each method is simple, effective, and guided by your care team for safety and comfort.
Clean the vial’s rubber top with an alcohol swab. Attach a drawing needle to your syringe, then pull back to draw in air equal to your dose. Insert the needle into the vial and push the air in (to prevent vacuum). Invert the vial, slowly draw the medication to the desired dose, tap out air bubbles (if needed). Swap to a fresh injection needle before administering for. Some needles may use a separate syringe to draw medication and then twist off to attach a new syringe to inject.
Clean the injection site with an alcohol swab. Pinch the skin for subcutaneous (Subq) injections or stretch it flat for intramuscular (IM) injections. For IM injections it's best to relax the muscle while injecting. Insert the needle at the appropriate angle (45° for subQ, 90° for IM), inject the medication slowly and steadily, then withdraw the needle. There should be no blood after the syringe is removed but don't worry if there is a little. Dispose of the needle in a sharps container, and wash your hands.
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